Conan Christopher O'Brien Was born on April 18th 1963, is an American television host, comedian, writer, producer, musician, and voice actor. Conan O'Brien is best known for hosting several late-night talk shows, the most recent of which, Conan, premiered on American cable television station TBS in 2010. Conan O'Brien was born in Brookline, Massachusetts, and was raised in an Irish Catholic family.